Treating Resistant Hypertension With a Neglected Old Drug

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Treating resistant hypertension with a neglected old drug.

Hypertensive patients are said to be resistant to therapy when their pressures exceed goal despite treatment with 3 antihypertensive drugs. The tendency of most clinicians is to treat resistant patients with stronger and stronger agents in higher and higher doses. By contrast, a few reports in the literature suggest surprising usefulness of spironolactone, a relatively weak diuretic, in resista...

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Treating hypertension in the very old.

Hypertension is prevalent and accounts for a large proportion of cardiovascular morbidity and mortality worldwide.1 There is a continuous, approximately linear, increase in systolic blood pressure with increasing age in developed and developing nations in both men and women and in most races and ethnic groups.1,2 The level of blood pressure is related to the risk of stroke, ischemic heart disea...

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Treating resistant hypertension: role of renal denervation

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ژورنال

عنوان ژورنال: Hypertension

سال: 2007

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.0000259806.91169.01